Once you have installed the profile to your computer, restart the program you are designing your ad in. You can then convert the images in your advert to the correct ICC Profile.
Take the images from your advert into Photoshop. Make sure all the layers are flattened.
In Edit (in the toolbar dropdown) select Convert to Profile. (Make sure you do not select Assign Profile as this is not the same thing and will not convert the colour correctly.)
A screen will pop up with a drop down field named Destination Space.
From the dropdown, select the correct profile, and click OK.
You then go back into the program you are creating your artwork in, replace the converted images and re-export your PDF.
Edit -> Save As -> Color: Embed Color Profile: Isonews.... need to be tick.
For any further questions, please contact the Specle Support Team
at firstname.lastname@example.org or call us on 020 7871 3555